skin radiance



CLOTHOLINE® stimulates skin cell longevity by activating the Klotho protein, which is known as the “youth protein”.

Klotho is drawing increasing interest from cosmetic R&D departments and has enabled a better understanding of the aging process.

By increasing the expression of Klotho in skin cells, CLOTHOLINE® allows to preserve the skin from the natural aging process.
Skin firmness is maintained and skin tone becomes more harmonious and radiant. Users who apply CLOTHOLINE® over a longer period also report an increased sense of well-being.

CLOTHOLINE® is the first cosmetic ingredient to provide a quantified sense of well-being to users.


Well-being / Skin radiance / Anti-aging


Cornflower Centaurea cyanus
or Extraction or Green synthesis

inci (active)

CLOTHOLINE® LV : Centaurea cyanus flower extract, methylpropanediol. UL Prospector.

CLOTHOLINE® Green (COSMOS approved) : Centaurea cyanus flower extract, pentylene glycol, glycerin. UL Prospector.

CLOTHOLINE® BG : Coumaroyl Methoxytryptamine, Butylene Glycol

biological activity

Activates the Klotho youth protein
Controls cell renewal
Increases skin cell longevity
Maintains the synthesis of Collagen I and Elastin
Regulates inflammation mediators

clinical efficacy

Increases the sense of well-being
Harmonizes skin tone
Increases skin radiance
Restructures skin
Maintains skin firmness

Clotholine® Green is a raw material verified by ECOCERT Greenlife , conform to the COSMOS Standard.

Cosmetic tips & tricks


Incorporate at the end of the formula (T° < 40°c)
Very easy to incorporate
pH 5-7
Recommended dose: 1%


Translucent liquid
Slightly yellow to amber


Facial care
Body care

CLOTHOLINE® is a multi-active ingredient that supports strong cosmetic claims.


skin radiance



all sollice biotech's cosmetic actives

Sollice Biotech provides a large variety of cosmetic actives with a wide action range

All our cosmetic ingredients are tested with scientific rigor in respect of all applicable regulations. All our cosmetic claims are thoroughly researched and documented based on solid biological data.